Abstract
Pain can be defined as a somatic sensation of acute discomfort, a symptom of physical hurt or disorder, or even emotional distress. Inflammation on the other hand refers to the body’s ability to fight against things that harms it such as infections, injury and toxins. The use of medicinal plants for pain killers was dated from the advent of ethno pharmacology. It is a procedure by which larger or greater of population get to access treatment for sickness, infection and other health related problems. This research therefore focuses on ascertaining the analgesic potentials of the plant Sarcocephalus latifolius. The roots of Sarcocephalus latifolius was obtained from Zuru Local Government Kebbi state Nigeria. The sample was washed with clean tap water and dried under room temperature before being pulverized into powdered form. The extract was subjected to phytochemical screening using laboratory standard method. The result of the phytochemical screening of the methanol root extract of S. latifolius revealed the presence of glycocides, alkaloids, terpenoids, flavonoids, phenols and carbohydrates while tannins and steroids were not detected. Similarly, Twenty five (25) albino rats divided into five (5) group of (5) each were used to assess the analgesic activity of S. latifolius. From the result obtained, the extract showed a dose dependent analgesic activity when compared to the negative control group. In conclusion, the results of this finding showed that S. Latifolius methanol root extract possesses analgesic activity which is mediated by inhibiting the synthesis of prostaglandin and reducing pain significantly thus it can be used as pain reliever in traditional medicine.

Key words: Analgesic, Methanol, Root, screening, Activity.