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2025, Vol: 7, Issue: 2
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Research Article
Online Published: 17 Aug 2025
 


ANTIOXIDANT AND ANTI-HEMOLYTIC ACTIVITY OF AQUEOUS LEAF EXTRACT OF Hibiscus sabdariffa AND METHANOL FRUIT EXTRACT OF Abelmoschus esculentus

Okwanya M.i., Anyebe A.d., Ide O.r., Mbaya Y.p..


Abstract
This study was designed to evaluate the in vitro antioxidant and anti-hemolytic activity of aqueous leaf extract of Hibiscus sabdariffa and methanol fruit extract Abelmoschus esculentus. They are both commonly consumed vegetables in Nigeria. The percentage inhibition of DPPH radical scavenging activity of the extracts and the standard ascorbic showed that the aqueous leaf extract of H. sabdariffa exhibited higher antioxidant activity than the A. esculentus methanol fruit extract. The IC50 of H. sabdariffa (2.81 mg/ml) was lower than A. esculentus (3.20 mg/ml) with respect to the standard ascorbic acid (2.29 mg/ml). The result from the FRAP assay also showed that extract of H. sabdariffa exhibited better antioxidant capacity than the A. esculentus extract. The IC50 of H. sabdariffa (2.97 mg/ml) was lower than A. esculentus (3.77 mg/ml) in comparison to ascorbic acid (2.01 mg/ml). Also, percentage inhibitions of anti-hemolytic activity of aqueous leaf extract of H. sabdariffa, methanol fruit extract A. esculentus, and the standard quercetin showed that the aqueous leaf extract of H. sabdariffa exhibited higher anti-hemolytic activity than the A. esculentus extract. The IC50 of H. sabdariffa (3.35 mg/ml) was lower than A. esculentus (3.89 mg/ml) in comparison to quercetin (1.96 mg/ml). From this study, H. sabdariffa extract could therefore potentially serve as a more suitable and potent agent against free radical mediated and hemolytic diseases.

Key words: H. sabdariffa, A. esculentus, Hemolysis, Antioxidant, Red blood cells


 
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How to Cite this Article
Pubmed Style

M.i. O, A.d. A, O.r. I, Y.p. M. ANTIOXIDANT AND ANTI-HEMOLYTIC ACTIVITY OF AQUEOUS LEAF EXTRACT OF Hibiscus sabdariffa AND METHANOL FRUIT EXTRACT OF Abelmoschus esculentus. JIRLS. 2025; 7(2): 1-8.

Web Style

M.i. O, A.d. A, O.r. I, Y.p. M. ANTIOXIDANT AND ANTI-HEMOLYTIC ACTIVITY OF AQUEOUS LEAF EXTRACT OF Hibiscus sabdariffa AND METHANOL FRUIT EXTRACT OF Abelmoschus esculentus. https://www.jirlsonline.com/?mno=277940 [Access: August 17, 2025].

AMA (American Medical Association) Style

M.i. O, A.d. A, O.r. I, Y.p. M. ANTIOXIDANT AND ANTI-HEMOLYTIC ACTIVITY OF AQUEOUS LEAF EXTRACT OF Hibiscus sabdariffa AND METHANOL FRUIT EXTRACT OF Abelmoschus esculentus. JIRLS. 2025; 7(2): 1-8.


Vancouver/ICMJE Style

M.i. O, A.d. A, O.r. I, Y.p. M. ANTIOXIDANT AND ANTI-HEMOLYTIC ACTIVITY OF AQUEOUS LEAF EXTRACT OF Hibiscus sabdariffa AND METHANOL FRUIT EXTRACT OF Abelmoschus esculentus. JIRLS. (2025), [cited August 17, 2025]; 7(2): 1-8.


Harvard Style

M.i., O., A.d., . A., O.r., . I. & Y.p., . M. (2025) ANTIOXIDANT AND ANTI-HEMOLYTIC ACTIVITY OF AQUEOUS LEAF EXTRACT OF Hibiscus sabdariffa AND METHANOL FRUIT EXTRACT OF Abelmoschus esculentus. JIRLS, 7 (2), 1-8.


Turabian Style

M.i., Okwanya, Anyebe A.d., Ide O.r., and Mbaya Y.p.. 2025. ANTIOXIDANT AND ANTI-HEMOLYTIC ACTIVITY OF AQUEOUS LEAF EXTRACT OF Hibiscus sabdariffa AND METHANOL FRUIT EXTRACT OF Abelmoschus esculentus. Journal of Innovative Research in Life Sciences, 7 (2), 1-8.


Chicago Style

M.i., Okwanya, Anyebe A.d., Ide O.r., and Mbaya Y.p.. "ANTIOXIDANT AND ANTI-HEMOLYTIC ACTIVITY OF AQUEOUS LEAF EXTRACT OF Hibiscus sabdariffa AND METHANOL FRUIT EXTRACT OF Abelmoschus esculentus." Journal of Innovative Research in Life Sciences 7 (2025), 1-8.


MLA (The Modern Language Association) Style

M.i., Okwanya, Anyebe A.d., Ide O.r., and Mbaya Y.p.. "ANTIOXIDANT AND ANTI-HEMOLYTIC ACTIVITY OF AQUEOUS LEAF EXTRACT OF Hibiscus sabdariffa AND METHANOL FRUIT EXTRACT OF Abelmoschus esculentus." Journal of Innovative Research in Life Sciences 7.2 (2025), 1-8. Print.


APA (American Psychological Association) Style

M.i., O., A.d., . A., O.r., . I. & Y.p., . M. (2025) ANTIOXIDANT AND ANTI-HEMOLYTIC ACTIVITY OF AQUEOUS LEAF EXTRACT OF Hibiscus sabdariffa AND METHANOL FRUIT EXTRACT OF Abelmoschus esculentus. Journal of Innovative Research in Life Sciences, 7 (2), 1-8.


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