Evaluation of Wound Healing Potentials of Tamarindus Indica Methanol Stem Bark Extract in Albino Rats

Abdulkarim Abba; Angela Nnena Ukwuani-Kwaja; Lukman Muhammad

2024, Vol: 6, Issue: 1

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Evaluation of Wound Healing Potentials of Tamarindus Indica Methanol Stem Bark Extract in Albino Rats

Abdulkarim Abba, Angela Nnena Ukwuani-Kwaja, Lukman Muhammad.

Abstract
The powdered form of Tamarindus indica stem bark is traditionally applied for the management of various infirmities that include diabetes, malaria, diarrhea, typhoid and wounds. The present study is aimed at providing scientific validation for the wounds restorative potential of Tamarindus indica methanol stem bark extract in the excision albino rats model. Maceration extraction was done using 100% solvent (methanol) and qualitative phytochemical analyses were carried out using standard methods. Excision wound methods was adopted to evaluate wound healing therapeutic potentials of Tamarindus indica. Phytoconstituents present were alkaloids, flavonoids saponins, cardiac glycosides, and quinones. Wounded rats were treated with ointment formulation of the extract (10% and 50% w/w) and penicillin cream for 24days. Wounds size reduction and rate of epithelization revealed a significant (P<0.05) dose-dependent increase in the extract-treated groups compared to normal control. Significant percentage (%) wound contraction in penicillin and extract-treated groups were seen on day 9. Findings of present study certify that crude extract of Tamarindus indica methanol stem bark extract possesses wound healing potentials. This justifies the ethnomedicinal use of this plant for the treatment of wounds and sores.

Key words: Woundhealing,epithelisation, stembark extract and wound contraction

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Pubmed Style

AA, ANU, Muhammad L. Evaluation of Wound Healing Potentials of Tamarindus Indica Methanol Stem Bark Extract in Albino Rats. JIRLS. 0; 0(0): 0-0.

Web Style

AA, ANU, Muhammad L. Evaluation of Wound Healing Potentials of Tamarindus Indica Methanol Stem Bark Extract in Albino Rats. https://www.jirlsonline.com/?mno=83818 [Access: January 07, 2024].

AMA (American Medical Association) Style

AA, ANU, Muhammad L. Evaluation of Wound Healing Potentials of Tamarindus Indica Methanol Stem Bark Extract in Albino Rats. JIRLS. 0; 0(0): 0-0.

Vancouver/ICMJE Style

AA, ANU, Muhammad L. Evaluation of Wound Healing Potentials of Tamarindus Indica Methanol Stem Bark Extract in Albino Rats. JIRLS. (0), [cited January 07, 2024]; 0(0): 0-0.

Harvard Style

, A. A., , . A. N. U. & Muhammad, . L. (0) Evaluation of Wound Healing Potentials of Tamarindus Indica Methanol Stem Bark Extract in Albino Rats. JIRLS, 0 (0), 0-0.

Turabian Style

, Abdulkarim Abba, Angela Nnena Ukwuani-Kwaja, and Lukman Muhammad. 0. Evaluation of Wound Healing Potentials of Tamarindus Indica Methanol Stem Bark Extract in Albino Rats. Journal of Innovative Research in Life Sciences, 0 (0), 0-0.

Chicago Style

, Abdulkarim Abba, Angela Nnena Ukwuani-Kwaja, and Lukman Muhammad. "Evaluation of Wound Healing Potentials of Tamarindus Indica Methanol Stem Bark Extract in Albino Rats." Journal of Innovative Research in Life Sciences 0 (0), 0-0.

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

, A. A., , . A. N. U. & Muhammad, . L. (0) Evaluation of Wound Healing Potentials of Tamarindus Indica Methanol Stem Bark Extract in Albino Rats. Journal of Innovative Research in Life Sciences, 0 (0), 0-0.


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